In 2024, I submitted a saliva sample to Ancestry.com to have my DNA analyzed. The following is my very basic understanding of genetics, the way these tests work and how to use the results for genealogical research. Needless to say, there have been many books written on these subjects so it can be very complicated.

 

Deoxyribonucleic acid (DNA) in our cells contains the genetic memory which passes all manner of traits from one generation to the next in our genes. Half of our DNA comes from our biological father and the other half from our biological mother. Although that percentage does not change, the specific factors in the DNA will be different from one child to another. That is why each of us is a unique human being.

We humans have about 20,000 genes and each of these has some type of influence on a particular trait in our bodies. A certain combination will result in brown hair or blue eyes or our height or whether we are more or less susceptible to certain types of cancer. It has only been in recent decades with expanded computing power that scientists have been able to map the human genome and identify the nature of our DNA.

 

Several million people around the world have taken a DNA test over the past couple of decades. Millions more now submit a sample for testing each year. Genetic scientists have been able to determine that, if two people share a certain percentage of their DNA, they must be related. Further, if they share around 50%, they must be full siblings. Grandparents, aunts, uncles, nieces and nephews would share about 25% of the same DNA while first cousins share about 12.5%. This can be carried out to where a 5th cousin may share 0.05% of their DNA.

Of course, in determining an exact relationship between two people had to take into account such things as the age of the individuals. For instance, a person who shares about 25% of your DNA but is only 2 years older than you father, is most likely an uncle and not your grandfather.

DNA testing companies will offer you the opportunity to get in touch with other people in their database who are related to you. You must first agree to allow your data to be available so that relatives may be able to contact you.

 

In the not too distant past, it would take many days of computer time to calculate the relationship of one person to others in the huge databases being built around the world. Now, the same problem can be completed in a relatively short time with current computer systems.

Companies that test DNA have analyzed huge amounts of data to discover patterns in DNA that can distinguish one population of people from another. For instance, Ancestry DNA compares over 700,000 different factors in a sample to find where even miniscule patterns exist between a given population and your DNA.